St. Louis Clinical Trials conducts ongoing trials for various conditions, including addiction related to pain management. Visit www.stlclinicaltrials.com or call 314-802-8822 for more information.

Dr. Ginger Nicol is currently conducting a study at the Washington University School of Medicine in St. Louis to test the effectiveness of a 17-week family-based behavioral weight loss program in overweight or obese youth who are treated with antipsychotic medications. This study is seeking overweight or obese (BMI percentile greater than or equal to 85) children 6 to 18 years old who are currently being treated with antipsychotic medications for one or more childhood onset psychiatric disorders.

Duration of the study is approximately 17 weeks. Child and caregiver will be interviewed by phone for eligibility. Screening and initial diagnostic assessments will occur in-person or by phone. Eligible participants will be randomized into one of two groups: 1) receive a weekly in-person diet and exercise intervention (through a family-based, behavioral weight loss program) or 2) a monthly diet and exercise education program. Medical assessments (including imaging, ECG, and blood tests) will occur at baseline and 17 weeks. 

There are no physical risks associated with the psychiatric diagnostic and assessment procedures or with the behavioral weight loss therapy provided in this study. There may be minimal risks associated with the blood draws and imaging procedures conducted in this study; these risks are the same as if your child was having a blood draw or imaging test ordered by a physician. 
Children will be screened for risk factors for serious medical conditions that may not show any symptoms, such as heart disease, stroke, and liver disease. If the child is overweight, he/she may also acquire skills to help improve his/her diet, activity level, and ultimately, he/she may lose weight and gain the health benefits that would accompany weight reduction.

Participants will receive reimbursement for their time and effort. Transportation can be provided as needed.

For more information, contact Julie Schweiger at 314- 362-3153 or This email address is being protected from spambots. You need JavaScript enabled to view it. or Vincent Huang at 314-362-5939 or This email address is being protected from spambots. You need JavaScript enabled to view it..

This study, designed to help understand how attention is related to symptoms of anxiety and depression is seeking children who are shy, worried, and/or clingy as well as children without these symptoms. If your child struggles with any of these symptoms and is 8-12 years old, you and your child may be eligible to participate in this research study.  Participants will be interviewed, complete video games and possibly have an fMRI scan during their 1 to 2 visits of up to 4 hours. After completing the study, parents will be mailed a letter stating any psychiatric diagnoses that their child meets research criteria for and recommendations for community mental health providers based on those diagnoses.  Participants will be compensated up to $100 per visit.

For more information or to complete the eligibility checklist, please contact Jennifer at at 314-286-2697 or This email address is being protected from spambots. You need JavaScript enabled to view it..

The purpose of this study at Washington Univeristy is to understand how the brains of healthy preschool children work and develop. Children will visit the Early Emotional Development Program offices for 1 (one) 2-1/2 hour visit, where they will play some games while their parent fills out some questionnaires. Children will also complete one EEG recording, where they will wear a special cap, play games, and win prizes.

For more information, contact Grace at 314-273-1045.

The Psychological and Brain Sciences Department at Washington University is looking for individuals between the ages of 18 and 49 to participate in a study that examines decision-making, learning and memory. Four types of participants are needed:

  • those with a diagnosis of bipolar disorder
  • those with a diagnosis of schizophrenia or schizoaffective disorder
  • those with a diagnosis of depression
  • those without any of the above diagnoses

The study involves three visits (including a brain scan) and a two-week period of responding to short questions throughout the day via a specialized cell phone provided through the study. Flexible scheduling and transportation available. For details regarding additional eligibility criteria, possible compensation and general information, call 314-935-8171.

The purpose of this study at Washington University is to help understand how the development of the characteristic of "overcontrol" is related to social relationships, moods, behaviors and symptoms of anxiety. Study is looking for children age 5 and 6 to visit the Early Emotional Development Program office for one visit, where parents will be interviewed and complete questionnaires, while children complete activities and play computer games while having an EEG. Participants will be contacted in two years for a follow-up session.

For more information, contact Kirsten at 314-747-0001 or This email address is being protected from spambots. You need JavaScript enabled to view it..

Psychiatric Care and Research Center conducts ongoing trials for various diagnoses, including fibromyalgia in adults. Visit www.pcrc-stl.com or call 636-244-3593 for more information.

Washington University is conducting an observational study, meaning no diagnostic evaluations are performed and no medication is provided or monitored as part of the study. The purpose is to better understand how difficulties with memory, thinking and motivation impact daily life and functioning when a psychiatric disorder is present. Participation includes two out-patient visits (each lasting between three and four hours), one visit to complete an fMRI brain scan, clinical interviews, computer tasks, and questionnaires. Compensation is available for completed tasks. Participants needed for this study:

  • must be between 18 and 49 years of age
  • must be diagnosed with schizophrenia, schizo-affective disorder, bipolar or major depression

Contact Katie Pereira at 314-935-8459 or This email address is being protected from spambots. You need JavaScript enabled to view it. for more information.

Psychiatric Care and Research Center conducts ongoing trials for various diagnoses, including Obsessive-Compulsive Disorder in adults. Visit www.pcrc-stl.com or call 636-244-3593 for more information.

Dr. Kevin Black (Washington University School of Medicine) is conducting a study with children who recently started experiencing tics. Initial qualifiying criteria is:

  • children between the ages of 5 and 10 with parent/guardian participation
  • children with tics that started less than 6 months ago

The study includes up to 6 visits, including annual follow-ups, MRI scans, and questionnaires and interviews. Compensation is provided for time and effort.

For more information, call Emily (314-362-2083) or Vicki (314-273-1876.

Midwest Research Group/St. Charles Psychiatric Associates is conducting a clinical trial of medication for children and adolescents, ages 5 through 17, who are diagnosed with Tourette's Syndrome. This study focuses on decreasing the core symptoms of motor and phonic tics issues.  The study lasts approximately 16 weeks, with an option of enrolling into an extension study for continued treatment. The investigational medication is NOT an antipsychotic, as the goal is to target core symptoms instead of treating the tics.

Participants in this study may receive study medication or placebo, physician consultation, travel expenses and compensation for their time.  No insurance required.

Please visit MidwestResearchGroup.com or call 636-946-8032 and speak with Nicole or text 636-486-1930 and complete a short form.

Midwest Research Group     4801 Weldon Spring Parkway #300     St. Charles, MO 63304

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